Medical grade liquid silicone rubbers (LSRs) are widely used for a broad range of implantable medical devices, including cardiovascular, neurological, urological, ophthalmic, and aesthetic applications. Typically, LSRs are used to fabricate cured devices outside the body, and then the devices are implanted via surgery.
Now, an in-situ LSR delivery system from Avantor’s NuSil brand allows for implantation of pre-sterilized materials for in-situ cure and forming within the body, making it possible for medical device manufacturers to customize the fit of implanted devices, as well as enabling less invasive implantation procedures.
Designed specifically to allow sterilization of uncured medical grade LSR, the NuSil brand packaging solution for in-situ curable LSR features a gas sterilizable double-cartridge dispensing system that can be prefilled with specific uncured LSRs.
Each cartridge has a gas-permeable plunger seal, designed to allow ethylene oxide sterilant gas to permeate through the plunger seal to sterilize the contents of the cartridge.
Key features of the packaging system include:
- Disposable syringes available in a variety of sizes – 5ml, 10ml, 25ml, 50ml, and 75ml
- One-step sterilization of LSR components and packaging
- Adaptable to a variety of injection technologies
- Engineered for use in complete surgical kits