Pioneering battery-free cardiac implants

CELTRO, founded in late 2019, is an innovative startup composed of heart rhythm medical doctors and semiconductor industry engineers and executives. The company aims to revolutionize how implants integrate with the human body by developing electronic devices that do not rely on external energy sources. CELTRO's first project focuses on creating a 3D-printed, battery-free pacemaker implant using advanced additively manufactured electronics (AME) technology.

The current landscape of medical implants

Existing medical electronic devices are powered by batteries or external energy transfers, which limits their lifespan and necessitates secondary replacement surgeries, bringing along costs and health risks. Implantable cardiac electronics are particularly constrained by traditional out-of-organ implant sites, which require long insulated wires (leads) to connect to cardiac tissue. These leads increase the risks of insulation defects, wire breaks, infections, and other vascular damage, leading to potential patient harm, repeated surgeries, and escalating healthcare costs.

Reimagining in-body electronics

CELTRO identified the need for a new approach to packaging electronic components for in-body use. The challenge was to create highly compact devices, such as a pacemaker with a diameter of only 4mm, that could be deployed through an endoscopic catheter pathway while maintaining durability and functionality.

Advanced manufacturing technology as a solution

To address this challenge, CELTRO partnered with Nano Dimension, leveraging their AME technology to develop small, durable, and highly efficient medical implants. The result is a pacemaker with no batteries or leads, operating on an ultra-low nano-watt power footprint and eliminating the need for additional surgeries. AME technology allowed CELTRO to iterate quickly, benefit from rapid prototyping, and reduce time to market while integrating miniaturization and novel production processes.

Looking to the future

© CELTRO | https://celtro.de/

CELTRO's next goal is to demonstrate that the cardiac implant can maintain heart rhythm without external energy sources, ensure successful catheter deployment, and prove long-term operational viability. Once these milestones are achieved, the company will move into the certification phase. CELTRO envisions a future where advanced in-body electronics facilitate predictive healthcare, reducing the need for invasive procedures and enhancing patient outcomes. The company is currently in the proof-of-concept stage and remains optimistic about the impact of its technology on the medical implant industry.

CELTRO's groundbreaking work promises to usher in a new era of medical implants, enhancing patient safety, convenience, and healthcare efficiency. By eliminating the need for batteries and leveraging the body's natural energy, CELTRO is setting the stage for transformative changes in how medical implants function and interact with the human body.

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“We are extremely excited by the progress we’ve made in the development and testing of our battery-free cardiac implant that has been enhanced using Nano Dimension’s AME technology.  We are optimistic in the prospects of creating a platform of next-generation in-body electronics that will help shape the future of the medical implant industry,” says Dr.-Ing Gerd Teepe, CELTRO co-founder & CEO.