#1 - Cleveland Clinic Top 10 Medical Innovations for 2022

Next Generation of mRNA Vaccinology: This landscape-changing technology has the potential to be used to manage some of healthcare’s most challenging diseases quickly and efficiently.

Advancements in the generation, purification, and cellular delivery of RNA have enabled the development of mRNA vaccines across a broad array of applications, such as cancer and Zika virus infection. The technology is cost-effective, relatively simple to manufacture, and elicits immunity in a novel way. Furthermore, the emergence of the COVID-19 pandemic demonstrated that the world needed rapid development of a vaccine that was deployable around the globe. Because of previous research that laid the groundwork for this technology, an effective COVID-19 vaccine was developed, produced, approved, and deployed in less than a year. This landscape-changing technology has the potential to be used to manage some of healthcare’s most challenging diseases quickly and efficiently.